Major advances for the screening of breast cancer

Major advances for the screening of breast cancer

Major advances for the screening of breast cancer

The researchers examined genetic data, including blood samples, from a combined 275,000 women, 146,000 of whom had been diagnosed with breast cancer.

While significant progress in the fight against breast cancer has been made, more needs to be done. Doctors hope the new information released from a study by an worldwide team of 550 researchers help them understand the genetic role of the disease.

"If I knew I had a high chance (of getting breast cancer). or if there were other indicators then I would have done something about it", she said.

Possessing a broken version of either of these genes is thought to account for as much as 10 percent of all breast cancers, and about 15 percent of ovarian cancers.

In what's being billed as the world's largest collective study on the genetics of breast cancer, researchers have discovered 72 new gene variants that appear to be responsible for increasing the risk of developing the disease. According to the American Cancer Society Cancer Facts & Figures 2017, an estimated 252,710 women in the United States will be diagnosed with breast cancer and 40,610 will die from the disease this year.

Another population-based study has shown that women with annual lifetime exercise activity levels exceeding the median activity level for active control subjects were found to have a 20% lower risk for breast cancer when compared to inactive women.

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U.S. co-author Professor Peter Kraft, from the Harvard TH Chan School of Public Health, said the findings revealed a wealth of new information about the genetic mechanisms underlying the disease.

Early detection and aggressive treatments have seen a decline in deaths from the disease, with survival rates now at around 90 percent after five years.

"We get grant funding through pharmaceutical companies and donations like the New Brunswick Fire Department", said Dorothy Reed, president and co-founder of the Sisters Network "It's hard economic times for everyone so when somebody just gives you a donation it's really a blessing".

Those identified in the new studies are relatively common - some carried by one woman in 100 and others by more than half of all women.

Cambridge University and partners in a five-star global research alliance have identified seventy-two new genetic variants that contribute to the risk of developing breast cancer. "A better understanding of the biological basis of oestrogen receptor negative breast cancer may lead to more effective preventive interventions and treatments". Combining the genetic factors with hormonal and lifestyle influences was likely to increase the risk further, they said.

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