Ibuprofen Was Just Linked to Male Infertility

Ibuprofen Was Just Linked to Male Infertility

Ibuprofen Was Just Linked to Male Infertility

Scientists analyzed the hormones and blood of a group of 31 healthy white men between 18 and 35 years old over the course of six weeks. The bad news is the ibuprofen is one of a large class of related drugs that includes aspirin, and the likelihood that other drugs will have similar effects is high.

Ibuprofen is a popular over-the-counter drug used to alleviate pain, fever and inflammation - especially in cases of painful menstrual periods, migraines and rheumatoid arthritis.

Richard Quinton, MD, from Newcastle University in England and the Society for Endocrinology, says: "This is a landmark study that elegantly combines clinical and basic research, at both tissue and cellular levels, to show that ibuprofen, a common over-the-counter painkiller, can reversibly hinder testosterone production by testicular cells".

Though the exact reasons for the decline are not yet known; in a recent study, researchers have linked male infertility to Ibuprofen - a common painkiller.

Ibuprofen has been linked to fertility problems in men.

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In addition to producing sperm, the testicles secrete testosterone, the primary male sex hormone. That works out to three ibuprofen tablets per day if you're taking a typical 200mg/tablet product.

The team of investigators from Denmark, France and China found that within two week these men had an elevated risk of compensated hypogonadism, "a condition prevalent among elderly men and associated with reproductive and physical disorders", researchers note. In 2017, the NSAID that goes by brand names including Motrin and Advil raises the risk of heart attacks. This indicates that they had developed a condition called "compensated hypogonadism", which happens when testosterone production is reduced, but the body is able to compensate by increasing LH levels, the researchers said.

The safety and efficacy of active ingredients in these products has been well documented and supported by decades of scientific study and real-world use.
This amount was used to represent the dose taken by athletes to manage pain.

Bernard Jégou, a senior author on the study at the French National Institute of Health and Medical Research, said he saw no problem in people taking ibuprofen to alleviate pain in the short term - for toothache, for example - but warned against taking the drug for months on end if it was not strictly necessary.

The findings are certainly significant, as the 1,200mg of ibuprofen given to the participants each day is far below the suggested daily maximum of 3,200mg per day.

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